Research Professor at the Research Institute of Pharmaceutical Sciences at the University of Mississippi
Not Clearly Pro or Con to the question "Should Marijuana Be a Medical Option?"
"Cannabis as a smoked product, in my judgment, would not be a useful product simply because of the lack of standardization, the fact that it's a smoked material: you can't determine the dose, people smoke in different ways, plus the interaction of the many different components and degradation products, and the tars associated with smoked materials. So smoking is not a good delivery system.
However, cannabis as a plant that is rich in chemical components, would have potential for producing useful drugs, for example THC. Now THC in the oral preparation, it doesn't seem to be doing the good job it should or was expected to. My personal view on the reason for this is the 'first-pass effect.' The material taken orally goes through the liver and is converted to the 11-hydroxy metabolite, which is 4-5 times more potent in terms of psychoactivity, before getting into the bloodstream, and the profile of these two drugs is quite different."
Interview with Journal of the International Hemp Association, Dec. 19, 2005
Experts PhD's and JD's (lawyers) with significant post-doctoral involvement in medical marijuana issues; judges who have presided over medical marijuana cases. [Note: Experts definition varies by site.]
Involvement and Affiliations:
Research Professor at the Research Institute of Pharmaceutical Sciences, University of Mississippi
Professor of Pharmaceutics, University of Mississippi
President and Founder, ElSohly Laboratories, Inc.
Assistant Director of Physical Sciences, University of Mississippi, 1976-1988