Last updated on: 9/15/2011 | Author:

What Is Cannabidiol (CBD)?

General Reference (not clearly pro or con)

Teresa Iuvone, PhD, Professor of Experimental Pharmacology at the University of Naples Federico II, et al., wrote in their 2004 paper “Neuroprotective Effect of Cannabidiol, a Non-psychoactive Component from Cannabis Sativa, on B-amyloid-induced Toxicity in PC12 Cells” in the Journal of Neurochemistry:

“Cannabinoids are a group of… compounds occurring in the glandular hairs of Cannabis sativa (Indian hemp) and consequently in hashish and marijuana… Cannabidiol, the main component of the glandular hairs (up to 15%), is a non-psychoactive cannabinoid; it exerts a plethora of pharmacological effects, including anti-convulsive, sedative, hypnotic, anti-psychotic, anti-nausea and anti-inflammatory actions. Cannabidiol is a potent antioxidant compound and it has been recently proposed to have a neuroprotective role…”

2004 - Teresa Iuvone, PhD, an informational website and search engine, wrote in its article “What Is Cannabidiol?” (accessed Sep. 26, 2011):

“Cannabidiol is a cannabinoid and a major component of the cannabis plant, or marijuana plant. By itself, cannabidiol lacks the psychoactive effects most commonly associated with marijuana use yet still retains many of the medicinal benefits, such as its anti-seizure and anti-inflammatory effects. The legal status of cannabidiol varies from country to country. In the United States, for instance, it and all other phytocannabinoids are classified as Schedule I controlled substances, making possession or ingestion illegal.”

Sep. 26, 2011 - WiseGEEK  

The International Association for Cannabinoid Medicines, an international non-profit cannabinoid association, wrote in its “Cannabidiol” page on the website (accessed Sep. 28, 2011):

“CBD, or cannabidiol, is the major non-psychotropic cannabinoid found in Cannabis. It has shown anti-epileptic, anti-inflammatory, anti-emetic, muscle relaxing, anxiolytic, neuroprotective and anti-psychotic activity and reduces the psychoactive effects of THC [D9-tetrahydrocannabinol, the primary psychoactive ingredient in marijuana]. The mode of action of cannabidiol is not fully understood and several mechanisms have been proposed…”

Sep. 28, 2011 - International Association for Cannabinoid Medicines  

Project CBD, a non-profit educational service dedicated to promoting and publicizing research into the medical utility of cannabidiol, wrote in its “About Cannabidiol” page on the website (accessed Sep. 28, 2011):

“Cannabidiol —CBD— is a compound in Cannabis that has medical effects but does not make people feel ‘stoned’ and actually counters some of the effects of THC…

Scientific and clinical studies indicate that CBD could be effective in easing symptoms of a wide range of difficult-to-control conditions, including: rheumatoid arthritis, diabetes, alcoholism, PTSD, epilepsy, antibiotic-resistant infections and neurological disorders. CBD has demonstrated neuroprotective effects, and its anti-cancer potential is currently being explored at several academic research centers in the U.S. and other countries.”

Sep. 28, 2011 - Project CBD