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John Brust, MD, Professor of Clinical Neurology at Columbia University, et al., concluded in their 1990 study "Illicit Drug Use and the Risk of New-onset Seizures," published in the American Journal of Epidemiology:

“Marijuana use appeared to be a protective factor against first seizures in men…

Marijuana contains numerous cannabinoid compounds that differ in convulsant and anticonvulsant properties. Anticonvulsant properties were first noted in the 15th century, yet studies in humans have been few…

The authors conclude that heroin use is a risk factor and marijuana use a protective factor for new-onset seizures.”

1990