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The Institute of Medicine published in its Mar. 1999 report titled "Marijuana and Medicine: Assessing the Science Base":

“In fact, most drug users do not begin their drug use with marijuana–they begin with alcohol and nicotine, usually when they are too young to do so legally…

There is no evidence that marijuana serves as a stepping stone on the basis of its particular physiological effect.”

Mar. 1999 - “Marijuana and Medicine: Assessing the Science Base”