Ethan Russo, MD, Senior Medical Advisor at the Cannabinoid Research Institute, in a 2001 article "Hemp for Headache: An In-Depth Historical and Scientific Review of Cannabis in Migraine Treatment," published in the Journal of Cannabis Therapeutics, wrote:

“In closing, a unique dance of medical science and politics is occurring that will soon decide whether herbal cannabis (a derivative, or synthetic analogue) will rise like the legendary phoenix to resume an ancient role as a remedy for migraine and neuropathic pain.”