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Simon Lal, MD, PhD, Gastroenterologist at Spire Manchester Hospital and Spire Manchester Clinic Hale (England), et al. stated the following in their Oct. 23, 2011 European Journal of Gastroenterology and Hepatology article, "Cannabis Use amongst Patients with Inflammatory Bowel Disease":

“Patients with UC [ulcerative colitis], in particular, reported using cannabis to improve diarrhoeal symptoms, and, again, this perceived benefit has received mechanistic support from studies that suggest that cannabinoids inhibit intestinal secretory responses… It is equally plausible to speculate that patients perceived benefit from using cannabis to reduce pain and/or diarrhoea because the drug has a direct anti-inflammatory effect on intestinal tissue… As in other diseases, a significant proportion of both UC and CD patients reported using cannabis to enhance appetite, and the drug’s orexigenic properties are well-recognized, with many individuals commonly reporting appetite stimulation or ‘the munchies’ after use.”

Oct. 23, 2011