Clinical Neurologist at the Peninsula Medical School at the University of Plymouth, UK
Not Clearly Pro or Con to the question "Should Marijuana Be a Medical Option?"
"BACKGROUND: Disabling tremor is common in patients with multiple sclerosis (MS). Data from animal model experiments and subjective and small objective studies involving patients suggest that cannabis may be an effective treatment for tremor associated with MS. To our knowledge, there are no published double-blind randomized controlled trials of cannabis as a treatment for tremor in MS patients...
RESULTS: Analysis of the data showed no significant improvement in any of the objective measures of upper limb tremor with cannabis extract compared to placebo. Finger tapping was faster on placebo compared to cannabis extract (p < 0.02). However, there was a nonsignificant trend for patients to experience more subjective relief from their tremors while on cannabis extract compared to placebo.
CONCLUSIONS: Cannabis extract does not produce a functionally significant improvement in MS-associated tremor."
"The Effect of Cannabis on Tremor in Patients with Multiple Sclerosis," Neurology, Apr. 2004
Key Experts Physicians [Physicians are the "key experts" in the medical marijuana debate because the issue is thought by many to be ultimately based on the medical value and risks of marijuana, and Physicians, with their training and clinical work, should (at least in theory) have the best knowledge of marijuana's medical value and risks.] [Note: Key Experts definition varies by sites that have this designation.]
Involvement and Affiliations:
Clinical Neurology, Peninsula Medical School, University of Plymouth, Plymouth, UK
Research Registrar, Cannabinoids in Multiple Sclerosis (CAMS) Study Team
Cowrote "Cannabinoids in Multiple Sclerosis (CAMS) Study, Safety and Efficacy Data from Up to 12-months Follow-up," Journal of Neurology, Neurosurgery, and Psychiatry, 2005
Cowrote "Cannabis for Dyskinesia in Parkinson Disease: a Randomised Double-blind Crossover Study," Neurology, 2004
Cowrote "The Use of Cannabinoids for the Treatment of Spasticity and Other Symptoms Related to Multiple Sclerosis - Results of a Multicentre Randomised Placebo-controlled Trial (the CAMS Study)," Lancet, 2003
Cowrote "Cannabis for Multiple Sclerosis," Practical Neurology, 2002